منابع مشابه
Bone cell interactions through Eph/ephrin
Bones cannot properly form or be maintained without cell-cell interactions through ephrin ligands and Eph receptors. Cell culture analysis and evaluation of genetic mouse models and human diseases reveal various ephrins and Eph functions in the skeletal system. Migration, attachment and spreading of mesenchymal stem cells are regulated by ephrinB ligands and EphB receptors. ephrinB1 loss-of-fun...
متن کاملCell interactions in bone tissue engineering
Bone fractures, where the innate regenerative bone response is compromised, represent between 4 and 8 hundred thousands of the total fracture cases, just in the United States. Bone tissue engineering (TE) brought the notion that, in cases such as those, it was preferable to boost the healing process of bone tissue instead of just adding artificial parts that could never properly replace the nat...
متن کاملCorrection: Wise Regulates Bone Deposition through Genetic Interactions with Lrp5
In the Materials and Methods section, under the subheading ''Animal Care and Usage'', the protocol number approved by the Institutional Animal Care and Use Committees of the Stowers Institute for Medical Research is incorrect. The correct protocol number is RK Protocol ID: 2013-0114. Copyright: ß 2014 The PLOS ONE Staff. This is an open-access article distributed under the terms of the Creative...
متن کاملWise Regulates Bone Deposition through Genetic Interactions with Lrp5
In this study using genetic approaches in mouse we demonstrate that the secreted protein Wise plays essential roles in regulating early bone formation through its ability to modulate Wnt signaling via interactions with the Lrp5 co-receptor. In Wise-/- mutant mice we find an increase in the rate of osteoblast proliferation and a transient increase in bone mineral density. This change in prolifer...
متن کاملBone and Prostate Cancer Cell Interactions in Metastatic Disease. Authors
Institutions 1. School of Medicine, University of Queensland, Brisbane, Queensland, Australia 2. Department of Urology, Princess Alexandra Hospital, Brisbane, Queensland, Australia 3. School of Life Sciences and Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia 4. Centre for Diabetes and Endocrine Research, Princess Alexandra Hos...
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ژورنال
عنوان ژورنال: Cell Adhesion & Migration
سال: 2012
ISSN: 1933-6918,1933-6926
DOI: 10.4161/cam.20888